Central nervous system disorders

VII./4.3.: Workup

Meningiomas diagnosed with neuroimaging and due to their localisation determined by symptoms, but they are often accidental finding presented by MRI or CT scans performed because of other indications. Typical imaging finding and PET result make other diagnostic methods nearly useless; cerebrospinal fluid is normal, biopsy seldom needed. Histology of the meningiomas cannot be judged by their radiological appearance, but grade I slowly progressive meningiomas usually present with homogenous contrast enhancement, smooth surface and inner calcification, and show iso- hypointensity on T1 MRI images. Cystic meningioma, hyperostosis or destruction of the adjacent skull, penetrating through the skull base, hypervascularisation or surrounding oedema may refer to Grade II or III meningioma.